37 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Risk factor for Late ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis ... #signs #symptoms
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... hyperglycemic crises ... diabetes Key signs ... Pathophys #EM #IM
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
URT inflammation causes ... & seizures are late ... bacteremia are late ... Immunization #peds #pediatrics ... #pathophysiology
Newborn Assessment - APGAR Score

Assessment of newborn vital signs following labor via a 10-point scale evaluated
newborn vital signs ... remains low at later ... develop long-term neurologic ... Diagnosis #Peds #Pediatrics
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... prior to growth plate ... • Other rare causes ... Overproduction #diagnosis #signs ... endocrinology #pathophysiology
Causes of Apparent Life Threatening Event (ALTE) - Differential Diagnosis Algorithm
Cardiac:
 • Congenital Heart Disease
 •
Causes of Apparent ... Threatening Event (ALTE ... Disturbances Neurologic ... Diagnosis #Algorithm #Causes ... #Peds #Pediatrics
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
conditions that cause ... Pathophysiology: ... pregnancy, or other causes ... It's typically a late ... #peritonitis #IM
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... , vomiting • Late ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds #pediatrics
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... Brudzinski's sign ... Passive neck flexion causes ... While the pathophysiology ... #PhysicalExam #Pediatrics
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... dermis Clinical Signs ... - Erosions and crusts ... feasible CMC IM