10 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... proliferation rate ... #TLS #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Imaging: CXR- pulmonary ... organ dysfuxtion, ICU
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
Pathophysiology: ... is not diagnostic ... It's typically a late ... #peritonitis #IM ... #FM #ICU #surgery
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of poor perfusion ... Signs of congestion ... with presence of pulmonary ... acute coronary syndrome ... #criticalcare #icu
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... the underlying pathophysiology ... and cauda equina TREATMENT ... intensive care unit (ICU ... Hospital of Baltimore IM
Abnormalities in Rate and Rhythm of Breathing 
Normal 
The respiratory rate is about 14—20 per min
hyperventilation syndrome—a ... Occasional sighs ... Breathing #Patterns #Pulmonary ... Abnormalities #Abnormal #Diagnosis ... #PhysicalExam
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Differential Diagnosis ... • Mutism Pathophysiology ... • Examine for signs ... • If ok with ICU ... caseyalbin #PhysicalExam
Compartment Syndrome Pearls
A vicious cycle of increased pressure within a facial compartment leading to compression of
Compartment Syndrome ... Pathophysiology: ... , the rest are late ... signs. ... onset of ischemia Treatment
Hepatopulmonary Syndrome - Illness Script
HPS is a pulmonary disorder of chronic liver disease characterized by a
abnormalities PATHOPHYSIOLOGY ... the left heart TREATMENT ... HPS mortality rate ... only definitive treatment ... #cirrhosis #diagnosis
Cryptococcal meningitis on T2 MRI
30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Diagnosis? ... of prior silent pulmonary ... organism (soap bubble sign ... Standard treatment ... drained at time of diagnosis