216 results
Treatment of Syphilis
Early:
 • Penicillin G, 2.4 million units IM once OR
 • Doxycycline 100mg BID
Treatment of Syphilis ... million units IM ... BID for 2 weeks Late ... million units IM ... BostonChiefs #Syphilis
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Without treatment ... soles in 50% of cases ... and nephrotic syndrome ... Syphilis - Late ... Latent #Tertiary #Diagnosis
Causes of Erythema Nodosum - Mnemonic

NO cause found in 60% of cases
Drugs (antibiotics e.g., sulfonamides, amoxicillin)
Oral
Causes of Erythema ... Mnemonic NO cause ... Sarcoidosis or Lofgren's syndrome ... Psittacosis, Bartonella, Syphilis ... #Differential #Diagnosis
Syphilis - CDC 2021 Treatment Guidelines
Recommended Regimen:
 • Primary, secondary, and early latent: adults (including pregnant
Treatment Guidelines ... million units IM ... single dose • Late ... million units IM ... #CDC #CDC2021 #Treatment
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
with or without treatment ... , but without treatment ... the latent and late ... resembling rashes caused ... #Rash #Diagnosis
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
responsible for most cases ... Albuminuria, nephrotic syndrome ... infection • Late ... early latent • Late ... #stages #diagnosis
Genital Lesions - Differential Diagnosis Algorithm
Elevated - Vesicles:
 • Herpes simplex
Elevated - Papules / Plaques -
- Differential Diagnosis ... • Secondary Syphilis ... (condyloma lata ... ) • Reiter's syndrome ... #Algorithm #causes
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
HIV, Hepatitis, Syphilis ... Paraprotein-associated (POEMS syndrome ... Willis via UNC IM ... #differential #diagnosis ... #causes #neurology
Hyperthermia Syndromes Comparison
Serotonin Syndrome - NMS - Malignant Hyperthermia - Malignant Catatonia
Cause - Onset - Vitals
Hyperthermia Syndromes ... Comparison Serotonin Syndrome ... Malignant Catatonia Cause ... Mental Status - Treatment ... #Comparison #diagnosis
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... Guillain-Barré syndrome ... Hyperthyroidism, Serotonin syndrome ... , Eclampsia, Late ... #differential #diagnosis