46 results
Treatment of Syphilis
Early:
 • Penicillin G, 2.4 million units IM once OR
 • Doxycycline 100mg BID
Treatment of Syphilis ... million units IM ... BID for 2 weeks Late ... million units IM ... BostonChiefs #Syphilis
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
HIV, Hepatitis, Syphilis ... Inflammatory/AI: CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... Willis via UNC IM ... differential #diagnosis #causes
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Without treatment ... soles in 50% of cases ... and nephrotic syndrome ... Syphilis - Late ... roots, causing a syndrome
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... Deep coma (any cause ... Guillain-Barré syndrome ... Hyperthyroidism, Serotonin syndrome ... , Eclampsia, Late
Syphilis - CDC 2021 Treatment Guidelines
Recommended Regimen:
 • Primary, secondary, and early latent: adults (including pregnant
Treatment Guidelines ... million units IM ... single dose • Late ... million units IM ... #CDC #CDC2021 #Treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Epidemiology: • 1-2 cases ... Pathophysiology ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
with or without treatment ... , but without treatment ... the latent and late ... lesions—Condyloma lata—on ... resembling rashes caused
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Manifestations and Treatment ... responsible for most cases ... Albuminuria, nephrotic syndrome ... infection • Late ... early latent • Late
Genital Lesions - Differential Diagnosis Algorithm
Elevated - Vesicles:
 • Herpes simplex
Elevated - Papules / Plaques -
• Secondary Syphilis ... (condyloma lata ... ) • Reiter's syndrome ... ) • Behcet's syndrome ... Diagnosis #Algorithm #causes
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
Anaphylaxis: Treatments ... prevention of late ... Treatment: • ... ) 1:1000 IM q5-10mins ... #Management #pathophysiology