118 results
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Primary Syphilis ... Without treatment ... and nephrotic syndrome ... Syphilis - Late ... Latent #Tertiary #Diagnosis
Syphilis Staging - Primary, Secondary, Latent and Tertiary - Timing and Features

Primary syphilis classically presents with
Syphilis Staging ... by condylomata lata ... into early and late ... infection and late ... #Diagnosis #Syphilis
Syphilis - CDC 2021 Treatment Guidelines
Recommended Regimen:
 • Primary, secondary, and early latent: adults (including pregnant
Treatment Guidelines ... million units IM ... single dose • Late ... million units IM ... #Primary #Latent
Treatment of Syphilis
Early:
 • Penicillin G, 2.4 million units IM once OR
 • Doxycycline 100mg BID
Treatment of Syphilis ... million units IM ... BID for 2 weeks Late ... million units IM ... BostonChiefs #Syphilis
Natural History of Syphilis
Primary - 2-6 weeks after infection
 • Chancre, Regional lymphadenopathy
Early Latent ≤ 1
Primary - 2-6 weeks ... 2 months after primary ... Hepatitis, Nephritis Late ... Neurosyphilis → Late ... #progression #diagnosis
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Stages of Syphilis ... Early Primary: ... Late Latent: • ... BostonChiefs #Syphilis ... symptoms #signs #diagnosis
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
1) Primary Syphilis ... Albuminuria, nephrotic syndrome ... infection • Late ... early latent • Late ... #stages #diagnosis
Genital Lesions - Differential Diagnosis Algorithm
Elevated - Vesicles:
 • Herpes simplex
Elevated - Papules / Plaques -
- Differential Diagnosis ... • Secondary Syphilis ... (condyloma lata ... ) • Reiter's syndrome ... - Painless • Primary
Evaluation of Secondary Hypertension
 • Primary aldosteronism - PRA, PAC
 • Renal artery stenosis - Renal
Hypertension • Primary ... fT4 • Cushing syndrome ... - Late-night salivary ... Mineralocorticoid excess syndromes ... Evaluation #workup #diagnosis
Treatment Recommendations for Syphilis in Non-Pregnant Adults by Syphilis Stage

Incubating Infection, Primary, Secondary, Early Latent Syphilis:
Treatment Recommendations ... Incubating Infection, Primary ... day for 14 days Late ... CDC2015 #Regimen #Primary ... #Latent #Treatment