23 results
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
(CPPD) Pathophysiology ... culture used to diagnose ... #Pseudogout #CPPD ... #Rheumatology # ... diagnosis #management
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... Crystals - “Pseudogout ... should have other symptoms ... Joint #Disorders #msk ... #Differential #Diagnosis
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease

 - Acute CPPD precipitation into the joint space ->
polyarticular arthritis ... #CPPD #Disease ... #Signs #Symptoms ... #Pathophysiology ... #Diagnosis
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
Pseudogout: pathogenesis ... #CPPD #Disease ... #Signs #Symptoms ... #Pathophysiology ... #Diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... constitutional symptoms ... induced (Gout/Pseudogout ... Lyme • Gout/Pseudogout ... #MSK #rheumatology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... states Pathophysiology ... culture used to diagnose ... Gout #Comparison #rheumatology ... #Diagnosis
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
to Joint Pain - Diagnostic ... ), RA, crystal disease ... = Worry about late ... #Joint #Pain #MSK ... #rheumatology #
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... ) - MSK Radiology ... (RA, CPPD) - Can ... diffuse chondral disease ... #msk #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
or nerve root Symptoms ... of Joint Disease ... #Joint #Pain #MSK ... #rheumatology # ... #differential #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... fluid • Gout or pseudogout ... Compensated polarized light ... dihydrate crystals (pseudogout ... sedimentation rate