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hematology oncology differential cll lymphocytic management adhesivecapsulitis algorithm arthritis classification clinical disorders erythematosus finger flexor frozenshoulder fungal hemeonc infections infectiousdiseases
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... splenomegaly), night ... Fevers • Drenching night ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... → fevers, night ... #oncology #hematology ... #hemeonc #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... • Drenching night ... #CLL #Chronic ... #diagnosis #workup
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
pattern of spread, B symptoms ... Treated Like Acute Leukemias ... Amy Chung, MD, MSc ... Classification #pathophysiology ... #Hematology #Diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... constitutional symptoms ... up with pain at night ... #Differential #Diagnosis ... #MSK #rheumatology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
tissue => Years later ... Severe, worse at night ... FrozenShoulder #pathophysiology ... #diagnosis #symptoms ... stages #staging #msk
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... 85% • < 50% in chronic ... infection) • Chronic ... Aspergillosis Pathophysiology ... shock • Mortality rate
Night Sweats - Differential Diagnosis Framework Night sweats are a nonspecific symptom that patients commonly experience and
Diagnosis Framework ... a nonspecific symptom ... • Lymphoma • Leukemia ... alcohol, heroin RHEUMATOLOGIC ... reflux disease • Chronic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sedimentation rate ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Marrow Failure • Chronic ... Myelogenous Leukemia ... • Hairy Cell Leukemia ... Myelodysplastic #Syndromes #diagnosis
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