44 results
Central Retinal Vein Occlusion (CRVO)
 - Pathophysiology not fully understood; possibly due to thrombus located in
Occlusion (CRVO) - Pathophysiology ... Second most common cause ... retinopathy) #Clinical ... #Ophthalmology ... #Fundoscopy #Central
Pathological Optic Disc Cupping

Note cup-to-disc ratio at least 0.8 (physiologic limit of 0.5).

Thinning of optic disc
Usual cause is glaucoma ... Glaucoma causes ... OpticDisc #Cupping #fundoscopy ... #ophthalmology ... #Clinical
Cotton Wool Spots

Caused by microinfarcts. Exploded ganglion cell axons extrude their axoplasm into retina. Long DDx:
Wool Spots Caused ... CottonWool #Spots #fundoscopy ... #ophthalmology ... #Clinical
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
& seizures are late ... Maternal viremia causes ... bacteremia are late ... #Immunization #peds ... #pediatrics #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... share the same pathophysiology ... prior to growth plate ... • Other rare causes ... endocrinology #pathophysiology
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Passive neck flexion causes ... While the pathophysiology ... meningitis, it has low sensitivity ... Sign #Meningitis #Clinical ... PhysicalExam #Pediatrics #Peds
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
Pathogenesis and clinical ... neovascularization seen on fundoscopy ... edema seen on fundoscopy ... MacularDegeneration #pathophysiology ... #ophthalmology
Neovascular membrane on Fundoscopy Ocular Examination

Neovascular membrane in a patient with late age-related macular degeneration

Dr. Sebastian
Neovascular membrane on Fundoscopy ... a patient with late ... #PhysicalExam #clinical ... #video #ophthalmology ... #Fundoscopy
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... Risk factor for Late ... Alzheimer's (99% of cases ... Alzheimer's (1% of cases ... AlzheimersDisease #Dementia #pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... enzyme 21-OHase causes ... , vomiting • Late ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds