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management hematology neurology algorithm aortoenteric biliary cholangitis cirrhosis comatose fistula hemeonc hemophagocytic hepatitis hlh injury leukostasis liver lymphohistiocytosis lysis myelitis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... proliferation rate ... #TLS #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... • Jaundice (later ... bile ducts Differential ... #workup #hepatology
Aortoenteric Fistula - Diagnosis and Management Summary Epidemiology: • Uncommon but life-threatening • Most common site of bowel connection
duodenum Clinical Signs ... • Should be on differential ... that precedes a later ... Pathophysiology: ... undergo EGD - Sensitivity
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... HBV, HCV, HEV, EBV ... synthesis rises later ... #hepatology
The Neurological Evaluation of a Comatose Patient Definition: • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... Diagnosis: • ... • Mutism Pathophysiology ... • Examine for signs ... caseyalbin #PhysicalExam
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Hyperreflexia develops later ... • Bilateral signs ... Brucellosis - Dengue, EBV ... management #neurology #differential
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... Infections (e.g., EBV ... Presentation • Common Signs ... Pathophysiology ... #Management #Hematology
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