12 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... proliferation rate ... #TLS #diagnosis ... #management #hematology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... Dermatomyositis) AKI - Pathophysiology ... Iinitial rate: 1 ... #Diagnosis #Management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
hyperthermia crisis (late ... sign) (→ 3-8) ... #Hyperthermia #Differential ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... • Jaundice (later ... bile ducts Differential ... #workup #hepatology
Aortoenteric Fistula - Diagnosis and Management Summary
Epidemiology:
• Uncommon but life-threatening
• Most common site of bowel connection
duodenum Clinical Signs ... • Should be on differential ... that precedes a later ... Pathophysiology: ... undergo EGD - Sensitivity
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... initiation • Differential ... Differentiation #Syndrome ... #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... sequences improve sensitivity ... Reversible course Differential ... Diagnosis: • ... #diagnosis #management
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... HBV, HCV, HEV, EBV ... synthesis rises later ... #hepatology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... features developing later ... conditions listed in differential ... #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Hyperreflexia develops later ... • Bilateral signs ... #management #neurology ... #differential