38 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... proliferation rate ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... initiation • Differential ... organ dysfuxtion, ICU ... #management #hematology
First-line therapies for Asthma, Asthma-COPD Overlap and COPD

The diagnosis of COPD, asthma, and ACO initially requires
specific tests, such as ... bronchoprovocation test, and sensitivity ... summary of the differential ... asthma-COPD overlap; ICS ... #Diagnosis #Management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... and Management ... • Hypocalcemia/Late ... #Diagnosis #Management
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
pancreatitis but can also ... Pathophysiology: ... It's typically a late ... #cullensign #em ... peritonitis #IM #FM #ICU
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... Dermatomyositis) AKI - Pathophysiology ... Iinitial rate: 1 ... #Diagnosis #Management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... features developing later ... conditions listed in differential ... #management
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Pulse Pressure - Differential ... Diagnosis and Pathophysiology ... fibrillation at a rate ... Acute Coronary Syndrome ... #Diagnosis #Pathophysiology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... vein: Budd-chiari syndrome ... HBV, HCV, HEV, EBV ... synthesis rises later
Aortoenteric Fistula - Diagnosis and Management Summary
Epidemiology:
• Uncommon but life-threatening
• Most common site of bowel connection
duodenum Clinical Signs ... • Should be on differential ... that precedes a later ... Pathophysiology: ... undergo EGD - Sensitivity