6 results
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
& Specificity: ... cut-offs defined in clinical ... & Specificity ... BAL GM does not differentiate ... Frozen ice-pops (in setting
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
Galactomannan Testing ... Sensitivity Specificity ... 96% • Higher specificity ... >90% (In most clinical ... in BAL does not differentiate
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
HIV/AIDS, CGD) Clinical ... Diagnosis and Testing ... Galactomannan sensitivity ... and low specificity ... Management #treatment #fungal
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
in HIV / AIDS - Differential ... should be based on clinical ... effect/Edema • EBV ... of serum CrAg testing ... comparable to CSF testing
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Putrid sputum/sour-tasting ... Prevotella • Fungal ... Lung Abscess Differential
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
antigen assay has a sensitivity ... and specificity ... Urinary antigen testing ... ASPERGILLOSIS • Aspergillus ... Aspergillosis Pathophysiology