17 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Localization of Renal ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... H+ secretion → Hypokalemia ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Algorithm Extra-renal ... loss (Diarrhea) Renal ... Bartter syndrome, Gitelman ... potassium #low #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... (renal potassium ... Sjögren syndrome, Renal ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Differential Diagnosis Renal ... Bartter syndrome and Gitelman ... with secondary, hypocalcemia ... hypomagnesemia Renal ... diagnosis #causes #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... gastrointestinal K loss • Renal ... • Renal tubular ... Bartter's syndrome, Gitelman's ... algorithm #causes #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
intake, Diuretics (late ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... Diagnosis #Algorithm #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... Before evaluating hypokalemia ... suggests extra-renal ... Bartter syndrome, Gitelman ... differential #potassium #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
intake, Diuretics (late ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... Diagnosis #Algorithm #Nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Villous adenoma Renal ... chewing tobacco, Renal ... diuretic use), Gitelman's ... differential #diagnosis #nephrology