16 results
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... intake, Diuretics (late ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... Diagnosis #Algorithm #nephrology
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Localization of Renal ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... intake, Diuretics (late ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... Diagnosis #Algorithm #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... → Hypokalemia Metabolic ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Algorithm Extra-renal ... Low intake • Metabolic ... loss (Diarrhea) Renal ... Bartter syndrome, Gitelman ... potassium #low #nephrology
Metabolic and Respiratory Acidosis and Alkalosis - Diagnostic Algorithm

Anion gap - MUDPILES: 
 - Methanol (formic
Metabolic and Respiratory ... - Salicylates (late ... Addison disease - Renal ... #Respiratory #Metabolic ... Recommended Text: Nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic ... Chloridorrhea Renal ... • Penicillins Renal ... Hypomagnesemia • Barrter's/Gitelman's ... MetabolicAlkalosis #NonGap #Nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
• Hypokalemia (renal ... Hypochloremic metabolic ... Sjögren syndrome, Renal ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
suggests extra-renal ... Pressure: - Metabolic ... Bartter syndrome, Gitelman ... Hippurate - Metabolic ... differential #potassium #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... intake, Diuretics (late ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... Diagnosis #Algorithm #Nephrology