35 results
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Diagnosis Algorithm ... due to high ACTH stimulating ... , only seen in PRIMARY ... findings (see algorithm ... #StimTest #Endocrinology
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis Algorithm ... Weakness, fatigue, nausea ... hormone (ACTH) stimulation ... baseline ACTH - Primary ... #endocrinology
Adrenal Insufficiency Algorithm - Cosyntropin Stimulation Test
T-1m: Baseline cortisol drawn
T0: 250 µg cosyntropin given IV
T30m: Repeat
Adrenal Insufficiency ... Algorithm - Cosyntropin ... Stimulation Test ... #Testing #Algorithm ... #endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... Diagnosis Algorithm ... unclear (often the case ... #ACTH #Stimulation ... #Test #Endocrinology
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm
Primary Adrenal Insufficiency:
 • Autoimmune primary adrenal insufficiency
 • Adrenoleukodystrophy,
Diagnosis Workup Algorithm ... Primary Adrenal ... • Autoimmune primary ... Diagnosis #Workup #Algorithm ... #endocrinology
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Primary vs Secondary ... Adrenal Insufficiency ... limited adrenal stimulation ... Secondary #Adrenal #Insufficiency ... Pathophysiology #endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal ... Insufficiency - ... Differential Diagnosis Algorithm ... ACTH-Independent (Primary ... #Causes #endocrinology
Breast Discharge - Differential Diagnosis Algorithm
High Prolactin + Normal TSH
 • Microprolactinoma
 • Steroid Hormone Intake
Differential Diagnosis Algorithm ... Pregnancy, Breast Stimulation ... + High TSH • Primary ... #Endocrinology ... #Causes
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Diagnosis Adrenal Insufficiency ... - Algorithm ... Differentiate primary ... #ACTH #Stimulation ... #Endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Test 1: Baseline AM Cortisol 
 - Beware of major normal value
 -
Adrenal Insufficiency ... Diagnosis Algorithm ... ) Test 2: ACTH Stimulation ... #Diagnosis #Algorithm ... #endocrinology