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diagnosis differential dermatology generalized oncology secondary systemic ckd classification common cvid gap globulin hemodialysis hodgkins hypogammaglobulinemia immunodeficiency immunology leukemia nephrology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Systemic and Primary Causes ... renal failure/uremia ... Differential: • Lymphoma ... #causes
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Skin Ulcers by Etiology ... cutaneous T-cell lymphoma ... • Factitious disorder ... • Sickle Cell Anemia ... #causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... renal failure/uremia ... Differential: • Lymphoma ... #causes
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Weight loss • Anemia ... • Pruritis ... classification #hematology ... #oncology #management
Management of Pruritus in Patients with Chronic Kidney Disease Pruritus with no primary lesions - differential diagnosis:
Management of Pruritus ... • Hematologic ... deficiency anemia ... and Non-Hodgkin lymphoma ... #Treatment #Algorithm
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... • Nodules • Lymphoid ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... sweats, bleeding • Pruritis ... - infiltrates (anemia ... CLL -> Invade Skin ... #Leukemia #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Amyloidosis • Lymphoma ... gammopathy, and skin ... Connective tissue disorders ... : Lymphoma, Leukemia ... Thalassemia, Sickle cell anemia
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
body (Autoimmune disorder ... • Inner ear • Skin ... Viral infection • Lymphoma ... Polychondritis #rheumatology ... #diagnosis #management
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