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hematology oncology rash blood differential hemophagocytic hlh lymphohistiocytosis product reactions anemia aplastic dress erythematous exanthematous generalized hemeonc infectiousdiseases leukemia leukostasis
ID Approach to Fever and Rash - Diagnostic Algorithm Central Maculopapular (most common): Measles, Parvovirus 819 / EBV,
WNV, Mycoplasma, Leptospirosis ... Secondary syphilis, EM ... angiomatosis, Sweet syndrome ... #Rash #Febrile ... #Diagnosis #Algorithm
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... redness of the skin ... syndrome (SSS) ... #Diagnosis #Dermatology ... #Nikolsky #Febrile
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Red Flags: • Fever ... • Extremes of age ... cryoglobulins • Skin ... #Algorithm #Causes ... #dermatology #physicalexam
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... characterized by fever ... Causes: - Idiopathic ... Leukemia cutis Diagnosis ... #diagnosis #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Fever >38.5 2. ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... 1) 4) Average age ... symptoms are not caused ... nodes: 13-15%, skin ... #Management #Signs
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - 80% have fever ... Treatment: - If febrile ... #TLS #diagnosis ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... < 3 months of age ... acute or subacute febrile ... following: • Fever ... #management #treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... Headaches • Pale skin ... recurrent infections/fevers ... and petechiae Causes ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Headaches, bone pain, fever ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Oncology #Diagnosis
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