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diagnosis neurology differential guillain rheumatology treatment anemia aplastic cerebritis cns common cvid erythematosus gbs gravis guillainbarre hypogammaglobulinemia immunodeficiency immunology lupus
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Demyelinating Disease (MS ... Poliomyelitis, Guillain-Barre ... syndrome, Mononeuritis ... heavy metals), Critical
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Epidemiology: • 1-2 cases ... Clinical Features ... #management #treatment ... #neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... transplantation CLINICAL ... #Syndrome #diagnosis ... #management #neurology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... CMV) • Epstein-Barr ... Anemia #oncology #hematology ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... DDX - Other causes ... infections (Epstein-Barr ... syndrome, HIV) ... hypogammaglobulinemia #immunology #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... #rheumatology # ... cerebritis #diagnosis #management
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Clinical Picture ... Clinical DX: - ... immunologic assay - MuSK ... Gravis #diagnosis #management ... #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... • Infectious causes ... Mycoplasma - Leptospirosis ... Myelitis #diagnosis #management ... #neurology #differential
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Diagnosis #Management
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