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diagnosis differential management infectiousdiseases treatment activetb cardiology endocarditis latenttb tb tuberculosis abscess aids aspergillus betadglucan biomarkers causes challenges criticalcare dehydrogenase
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
to Eosinophilic Lung ... , CNS, skin • Infectious ... (Variable) - Fungal ... #Diseases #pulmonary ... differential #diagnosis #comparison
Non-Resolving Pneumonias: Etiologies Unusual Infections: - Immunocompromised patients (e.g.: Mycobacterium, Aspergillosis, Nocardia) - Endemic Fungi (e.g.: Histoplasmosis,
Etiologies Unusual Infections ... Nocardia) - Endemic Fungi ... psittaci/avian, leptospirosis ... yersinia/rats, Q fever ... Others: - Pulmonary
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Illnesses: • Pulmonary ... Presentation: Fever ... Manifestations: • Fever ... • Fever and weight ... diagnosis • Microbiologic
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... (NTM) • Fungal ... • Lymphoma • Lung ... • Progressive lung ... Active TB: • Fever
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Pseudomonas FUNGAL ... cough, myalgia • Lung ... #Infections #HIV ... #AIDS #pulmonary
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... (NTM) • Fungal ... • Lymphoma • Lung ... • Progressive lung ... Active TB: • Fever
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) ... surfaces - Infections ... Clav (may be + as long ... post-2010 almost never ... Galactomannan #diagnosis #comparison
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... : • 80% have fever ... Intervention: - Fevers ... Prevotella • Fungal ... #Abscess #pulmonary
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Prosthetic valves Lung ... Legionnaires disease • Pulmonary ... Pneumonia • Other lung ... • Toxins • Infection ... myocarditis, rheumatic fever
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
verrucous) • Lung ... Hypercoagulable (APLAS) Microbiology ... night sweats, fever ... Cerebral > Splenic, pulmonary ... Persistent bacteremia/fevers
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