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diagnosis hematology chronic cll differentiation leukemia lymphocytic management syndrome workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Differential Diagnosis: Infection ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... weeks without infection ... lymphocyte > 5000/microL ... microglobulin Treatment ... diagnosis #workup #oncology
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