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diagnosis hematology management oncology chronic hemophagocytic lymphocytic lymphohistiocytosis anemia aplastic cancer classification differential hemeonc hodgkins lymphoma polychondritis relapsing summary thrombocytopenia
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Leukemia, Tumour ... ITP • SLE • CLL ... Alloimmune • anti-HLA ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Lymphadenopathy • Fevers ... microglobulin Treatment ... leukemia #CLL ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... : fever +++, hepatosplenomegaly ... Treatment: • ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... following: • Fever ... Low or absent NK cell ... • Bicytopenia Treatment ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... • Most common leukemia ... immunophenotype Clinical ... ) B symptoms → fevers ... #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Hodgkin Lymphoma - Clinical ... • Dyspnea • Fever ... Hodgkin Lymphoma Treatment ... classification #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... Presentation: • Fever ... and petechiae Causes ... virus (EBV) • Leukemia ... aplastic anemia Treatment
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... algorithm 2018. ... acute myeloid leukemia ... importance of clinical ... #algorithm #hematology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Males • Affects all ... the most common clinical ... Nonspecific symptoms: Fever ... affected tissue Treatment ... Polychondritis #rheumatology
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