9 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... triad: Fever, Arthralgia ... #AdultOnset #Stills ... #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... #Disease #AOSD ... #rheumatology #diagnosis ... #management #treatment
Chagas Disease (American trypanosomiasis) - Diagnosis and Management Summary
Acute Chagas Disease (8-12 weeks):
 • Mild: Malaise,
Chagas Disease ( ... Diagnosis and Management ... Mild: Malaise, fever ... • Treatment: ... #Microbiology #
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Treatment - Mild ... : NSAIDS Treatment ... #diagnosis #rheumatology ... #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Adult-onset Still ... • Periodic fever ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... +, Adult-onset Still ... disease, Infection ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Chagas Disease (American trypanosomiasis) - Diagnosis and Management Summary
Acute Chagas Disease (8-12 weeks):
 • Mild: Malaise,
Chagas Disease ( ... Diagnosis and Management ... Mild: Malaise, fever ... • Treatment: ... #Microbiology #
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
- Anasarca - Fever ... histopathologic changes ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management ... #rheumatology #
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
respiratory symptoms • Fever ... , cough, chills, ... pulmonary symptoms • Rheumatologic ... • Isolated fever ... Fungal #Diagnosis #Management