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diagnosis differential lung amiodarone comparison cop cryptogenic diseases eosinophilia eosinophilic fungal induced infections infectiousdiseases mycoses nonresolving organizing returning table toxicity
Non-Resolving Pneumonias: Etiologies Unusual Infections: - Immunocompromised patients (e.g.: Mycobacterium, Aspergillosis, Nocardia) - Endemic Fungi (e.g.: Histoplasmosis,
psittaci/avian, leptospirosis ... yersinia/rats, Q fever ... ) - Returning travelers ... Eosinophilic PNA (acute ... or chronic)
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Travelers from ... , acute HIV infection ... Cough, dyspnea - Pneumonia ... melioidosis, typhoid, pulmonary ... , Lassa fever, acute
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Lung Diseases • Acute ... Eosinophilic Pneumonia ... cough, SOB • Chronic ... Fungal, parasites; Travel ... Lung #Diseases #pulmonary
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
toxicity (e.g., acute ... • Chronic toxicity ... (e.g., chronic ... Fever 4. ... #diagnosis #management
Cryptogenic Organizing Pneumonia - Illness Script PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
/SYMPTOMS: • Acute ... Cough, dyspnea, fever ... identified (autoimmune, meds ... #diagnosis #management ... #pulmonary
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
conidia → Yeast → travel ... respiratory symptoms • Fever ... or chronic pulmonary ... • Isolated fever ... Fungal #Diagnosis #Management
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