19 results
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
confirmed the diagnosis ... , or Wolman’s disease ... and gut, which causes ... #clincial #peds ... NEJM #Wolmans #radiology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
and Pathophysiology ... • Severe iron deficiency ... coronary heart disease ... #Pathophysiology ... #causes #cardiology
Krabbe Disease 

Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
this interesting case ... Diagnosis was made ... leukodystrophy w/ deficiency ... #Diagnosis #MRI ... #Clinical #Radiology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
severe clinical ... due to chronic disease ... • Vitamin D deficiency ... #Differential #Diagnosis ... #Pathophysiology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Blood cultures • CXR ... ) • CXR upright
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... Cellular immune deficiency ... Drugs, Unknown cause
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases ... Clinical Signs ... decreased reflexes Pathophysiology ... tissue damage - CXR
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Pathogenesis and clinical ... • Inflammatory Disease ... retinal edema caused ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Framework NCPE Pathophysiology ... Causes include: ... acute cardiac disease ... ischemic changes CXR ... #cardiology