4 results
Cardiac Myocyte Contractile cycle
 - Ca2+ binds to TnC → TnI is inhibited → conformational change
Cardiac Myocyte Contractile ... allowing myosin to travel ... #Pathophysiology ... #Cardiology #Myocyte ... #Contraction
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... inotropy) ACCP Cardiology ... Classification #Classes ... #pathophysiology ... #phases #cardiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
repolarization - ↓ contraction ... Vaughan #Williams #Pharmacology ... Classification #Classes ... #pathophysiology ... #cardiology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... intracellular calcium causes ... contractility (force of contraction ... #cardiology