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differential causes abnormal aptt prolonged algorithm anticoagulant anticoagulation apixaban bleeding bruising cascade clot dabigatran dic disseminated edoxaban hemostasis inhibitor intravascular
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... Fibrinogen: ↓ • PT ... #diagnosis #causes ... #treatment #management ... #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
unfractionated heparin ... cause e.g. heparin ... Prolonged #Causes #diagnosis ... #differential #hematology ... #coagulation
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management ... hemoglobin/hemosiderin, Hepatic ... hemosiderin • PT ... #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... thrombin inhibitors, heparin ... Prolonged #Causes #diagnosis ... #differential #hematology ... #coagulation
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... thrombin #clot #PT ... #PTT #diagnosis ... #models #hematology ... Rivaroxaban #Edoxaban #heparin
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor of a coagulation ... Acquired: • Heparin ... #Differential #Diagnosis ... #Hematology
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