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oncology treatment anemia blood hemophagocytic hlh lymphohistiocytosis product reactions syndrome activation chronic classification cll hemeonc hodgkins hypertension leukemia leukostasis lymphocytic
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... if neutropenic fever ... #management #treatment ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Presentation: • Fever ... recurrent infections/fevers ... Anemia #oncology #hematology ... #diagnosis #management
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management ... Criteria: • Elevated ... present, symptoms, signs ... #Management #Summary ... #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... - Nonremitting fever ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... Diagnosis via genetic ... following: • Fever ... #management #treatment ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Portopulmonary Hypertension Presence of pulmonary arterial hypertension in a patient with portal hypertension No other obvious causes (chronic
m/s • Other signs ... for definitive diagnosis ... Diagnostic criteria ... #Hypertension #diagnosis ... #management #hepatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... Pure red cell aplasia ... workup #oncology #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... Sx include: fever ... due to marrow aplasia ... #Transfusion #diagnosis ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... lymph node biopsy (diagnostic ... through Ann Arbor criteria ... classification #hematology ... #oncology #management
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