16 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... accumulation of clinical ... Assessment • Clinical ... Unknown cause Treatment ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... can mimic common infections ... • Bicytopenia Treatment ... : • Infection ... #management #treatment
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... Coagulation Failure Infections ... Cirrhosis #Hepatology #gastroenterology ... #management #diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Clostridioides Difficile Infection ... and Management ... GrepMed Handbook Clinical ... #diagnosis #management ... #IDSA #gastroenterology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... HLH is a critical ... Triggers: â–ª Infections ... Clinical Presentation ... underlying trigger: Infections
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... hematology #oncology #management
Acute Dacryocystitis- A 4-week-old boy was brought to the emergency department after having drainage from both
He received a diagnosis ... dacryocystitis — infection ... the first day of treatment ... #NEJM #clinical ... #photo #peds #acute
Esophageal Necrosis
Etiology:
 - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events
 - Associated
antibiotic use, infections ... restored to esophagus Clinical ... third of esophagus Treatment ... : - Treatment of ... #management #gastroenterology
Tinea Capitis in a Newborn- A 3-week-old male newborn was brought to the pediatrician with three
capitis, a fungal infection ... ringworm, was diagnosed ... after 1 week of treatment ... #clinical #photo ... #NEJM #tinea #capitis