11 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Pain Rash ... infection Malar rash ... Vesicopustule on erythematous ... #dermatology #joint
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - with the skin ... Systemic Lupus Erythematosus ... (SLE), should have ... other symptoms ... like “butterfly rash
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... #systemic #erythematosus ... #signs #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... rash • Erythematous ... Arthritis: • Joint ... arthropathy • 90% joints ... Induced Lupus: • Symptoms
Lyme Disease: Clinical diagnosis. Likely if recent hiking, travel to endemic area, erythema migrans (EM), an
migrans (EM), an erythematous ... disease involving skin ... , joints, or Bell ... carditis, meningitis (see ... #LymeDisease #Symptoms
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... NPSLE rare, Malar rash ... constitutional symptoms ... Systemic Lupus Erythematosus ... Manifestations: Malar rash
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: erythematous nodules ... vesicular eruption - Joints ... mucositis - Rash ... Presentation - Systemic Symptoms ... vasculitis, and SLE
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
weakness without skin ... onset of muscle symptoms ... systemic lupus erythematosus ... (SLE), polymyositis ... myopathy #diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... : Erythematous nodules ... , mucositis • Rash ... • Progressive symptoms ... Palpable purpura, joint
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... with edema • Erythematous ... rash on the face ... interphalangeal joints ... Dermatomyositis #diagnosis #management