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hematology oncology treatment hemophagocytic hlh leukemia lymphohistiocytosis syndrome chronic cll dermatomyositis hemeonc lymphocytic product reactions stills activation adultonset anemia antimda5
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Arthralgia/arthritis, Skin ... Differential Diaqnoses ... #diagnosis #management ... #treatment #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Differential Diagnosis ... vasculitis (inflamed blood ... #rash #diagnosis ... #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... phenomenon CLL Diagnosis ... cells can indicate disease ... Lymphocytosis: Absolute blood ... workup #oncology #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
which can plug blood ... Cryofibrinogenemia Diagnosis ... Cryofibrinogenemia #diagnosis ... #rheumatology # ... hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Epidemiology: • Young adults ... response to local skin ... test (this is a skin ... #management #signs ... #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment ... #summary #rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... maculopapular skin ... anti-lL6R, anti-ILI #Adult ... #rheumatology # ... management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
arthritis (sJIA) • Adult-onset ... Still disease ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
common leukemia in adults ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... also observed in adults ... Diagnosis via genetic ... #management #treatment ... #hematology
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