11 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... - Mycoplasma, EBV ... , HIV, rubella legionella ... younger pts) Differential ... Disorders Such As
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... to repair DNA, as ... Anticonvulsants - Gold ... immunodeficiency virus (HIV ... hematology #diagnosis #management
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... , Anemia • Prevalence ... Crohn's > UC Anemia ... Receptor (sTfR) to differentiate ... Algorithm #diagnosis #management
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
/ AIDS - Differential ... should be based on clinical ... Inferomedial temporal lobes ... effect/Edema • EBV ... CNS #Infections #differential
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Progression: • Upper lobe ... characteristic features Clinical ... and quantiferon-gold ... staining, NAA (PCR ... TB #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Progression: • Upper lobe ... characteristic features Clinical ... and quantiferon-gold ... staining, NAA (PCR ... TB #Diagnosis #Management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Clinical ... Leukocytosis, anemia ... Clindamycin in case of PCN ... Coli - P. ... Lung Abscess Differential
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Excessive glutamate activity ... multiple spinal cord ... conditions listed in differential ... motor neurons - IV ... neurology #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... • PET scan - activity ... Immunohistochemical studies (to differentiate ... scans and can also ... hematology #oncology #management
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
Other +s: PCP, Histo ... positives: IVIG, IV ... >90% (In most clinical ... in BAL does not differentiate ... concurrent admin mold-active