8 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... - Mycoplasma, EBV ... , HIV, rubella legionella ... younger pts) Differential ... Disorders Such As
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
infection (NTM) • Fungal ... Progression: • Upper lobe ... characteristic features Clinical ... staining, NAA (PCR ... TB #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
infection (NTM) • Fungal ... Progression: • Upper lobe ... characteristic features Clinical ... staining, NAA (PCR ... TB #Diagnosis #Management
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
/ AIDS - Differential ... should be based on clinical ... Inferomedial temporal lobes ... effect/Edema • EBV ... CNS #Infections #differential
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
cut-offs defined in clinical ... products - IV ... BAL GM does not differentiate ... concurrent admin of mold-active ... Clav (may be + as
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
Other +s: PCP, Histo ... positives: IVIG, IV ... >90% (In most clinical ... in BAL does not differentiate ... concurrent admin mold-active
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Clinical ... Clindamycin in case of PCN ... Coli - P. ... Prevotella • Fungal ... Lung Abscess Differential
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Excessive glutamate activity ... multiple spinal cord ... conditions listed in differential ... motor neurons - IV ... neurology #diagnosis #management