10 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Syndrome (CAS ... Clinical Presentation ... - Mycoplasma, EBV ... younger pts) Differential ... #hematology #diagnosis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... should be based on clinical ... Inferomedial temporal lobes ... Demyelinating disease ... #Infections #differential
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... nervous system (CNS ... SLE], AOSD) • Infection ... with leukopenia, anemia ... Histopathologic criteria
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... fibromyalgia) • Infections ... and CNS • Headache ... lymphopenia, low PLT • Anemia
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
of right middle lobe ... Hematologic malignancy ... Bone Marrow - Anemia ... : • Clinical ( ... #differential #
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... Diagnostic Criteria ... Brucellosis - Dengue, EBV ... management #neurology #differential
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
infection • Family ... Hodgkin Lymphoma - Clinical ... number of sites of disease ... through Ann Arbor criteria ... classification #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Include: • Viral infections ... acute HIV, HBV, EBV ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential ... #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
(e.g., EBV) ... ▪ Autoimmune diseases ... - Cytopenias (anemia ... Diagnostic Criteria ... Diagnosis #Management #Hematology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Tenderness → Consider infectious ... • ANA < 20 % IBM ... : • PBC, autoimmune ... #differential #