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management hematology infections infectiousdiseases syndrome agglutinin anemia autoimmune behcet brain causes cold encephalopathy extrarticular fungal hemolytic hiv joint lesions monoclonal
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
Chorioretinitis • Diagnosis ... PCR 50% sensitive ... Lesions #Brain #differential ... #diagnosis #causes ... #radiology #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... Inferomedial temporal lobes ... Demyelinating disease ... #Infections #differential ... #diagnosis #AIDS
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... basal ganglia, CNS ... CNS symptoms (headache ... ) Differential Diagnosis ... signs #symptoms #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... Scleromyxedema (CNS ... #Monoclonal #Differential ... #Diagnosis #Oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome (CAS ... - Mycoplasma, EBV ... younger pts) Differential ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Extra-articular and Other Conditions ... syndrome - SLE Neurologic ... ear, sparing the lobe ... #joint #pain #differential ... #diagnosis #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
occipital and parietal lobes ... may precede the neurologic ... PRES-Associated Clinical Conditions ... Shock, Autoimmune disease ... Reversible course Differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... or as primary condition ... affects the skin, neurologic ... chorioretinitis, CNS ... #Diagnosis #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... yeast • At risk: AIDS ... transplantation • MCC ... especially the CNS ... MC: CNS CSF: •
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... RP-ILD), dermato-rheumatologic ... • ANA < 20 % IBM ... : • PBC, autoimmune ... #differential #
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