60 results
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
blocking effects and AP ... Action, ↑ EFR & AP ... Action, ↓ EFR & AP ... Action, ←→ EFR & AP ... Classification #Classes #pathophysiology
Autoimmune Gastritis - Pathophysiology

Anti-ParietaI Cell, CD4+ T Cells, Autoantibodies -> x Parietal Cells, x HCL, x
Autoimmune Gastritis - Pathophysiology ... Anti-ParietaI Cell, CD4 ... Autoimmune #Gastritis #Pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Action, ↑ EFR & AP ... Action, ↓ EFR & AP ... Action, ←→ EFR & AP ... phase 2 (↑ERP & ↑AP ... Classification #Classes #pathophysiology
The PET better demonstrates the extent of the lymphnode metastases in this patient.
Final diagnosis: small cell
extent of the lymphnode ... PET #APWindow #AP
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... , ↑Tbili/Dbili/AP ... diagnosis #management #pathophysiology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
IL-2 Muromonab-CD3 ... #Pharmacology #Pathophysiology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Difficile Infection (CDI ... Perforation) Pathophysiology ... x 10d • 1st CDI ... for recurrent CDI ... IDSA 2021 CDI
Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes
LifeCycle #diagnosis #pathophysiology ... infectiousdiseases #cdc
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
clearance - AP ... Bilirubin #Hepatology #Pathophysiology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
dendritic cell (DC ... activate naive CD4 ... #asthma #pathophysiology