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management pharmacology treatment infections antibiotics diagnosis hivaids opportunistic prevention algorithm guidelines table differential infectiousdiseases infection medications pneumonia tuberculosis bacterial clostridium
Outpatient Treatment of with Community-Acquired Pneumonia (CAP) No comorbidities or risk factors for MRSA or Pseudomonas aeruginosa:
doxycycline or • macrolide ... cephalosporin AND macrolide ... fluoroquinolone #IDSA
The 2007 Infectious Disease Society of America (IDSA)/American Thoracic Society (ATS) recommendations list macrolides as first
Society of America (IDSA ... recommendations list macrolides ... Resistance #Map #Macrolides
IDSA Recommendations for Treating Bartonella Infections in HIV-AIDS Preferred Therapy For Bacillary Angiomatosis, Peliosis Hepatis, Bacteremia, and Osteomyelitis:
IDSA Recommendations ... treatment: • A macrolide ... Bartonellosis #IDSA
Antibiotics for Atypical Bacteria - Macrolides (Azithromycin) - Tetracyclines (Doxycycline)
Atypical Bacteria - Macrolides
Antibiotic Classification by Mechanism of Action Cell Wall Synthesis: Penicillins Cephalosporins Carbapenems Monobactams Beta-lactamase inhibitors Glycopeptides Protein
Cloramphenicol Macrolides
Antibiotics and CNS Diffusion 1. Drugs with good CNS diffusion: - Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole 2. Drugs
Echinocandins, Macrolides
Classification of Some Antimicrobial Agents by Their Sites of Action Inhibitors of metabolism: Sulfonamides, Trimethoprim Inhibitors of cell
Aminoglycosides, Macrolides
Antibiotics - Mechanisms and Sites of Action Inhibit Cell Wall Synthesis or Function - Beta Lactams,
50S subunit - Macrolides
Common Medications Known to Prolong QTc Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide Vasopressors/inotropes - Epinephrine, norepinephrine,
Antibiotics - Macrolides
RHABDOMYOLYSIS • Characterized by skeletal muscle breakdown & necrosis. • Elevated Creatine kinase (CK) hallmark of rhabdomyolysis. • Defined based
: Daptomycin, macrolides
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