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Vesiculobullous Rashes - THE ALGORITHMIC APPROACH 
Vesiculobullous rashes provoke significant angst
in many physicians (Figure 5, page
Vesiculobullous Rashes - THE ALGORITHMIC ... and a fever may ... hand-foot-and-mouth disease ... localized lesions and fever ... #Diagnosis #Dermatology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
syndrome (SSS) in infants ... includes Kawasaki disease ... erythematous rash ... #Diagnosis #Dermatology ... #Febrile #Fever
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... with fever without ... CRP < 20 mg/L #Diagnosis ... Management #Pediatrics #Peds ... #Febrile #Infant
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... empiric antibiotic treatment ... 92.0% and 46.9% #Diagnosis ... #Febrile #Infant ... Stratification #Fever
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
in vasculitic diseases ... petechiae/purpura with fever ... the patient is afebrile ... #Diagnosis #Dermatology ... Purpural #Purpuric #Rash
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Onset Still's Disease ... extremities during febrile ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
frequently affects infants ... age, however the disease ... acute or subacute febrile ... following: • Fever ... #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome Acute febrile ... with systemic disease ... sudden onset of a rash ... - Rash: multiple ... Treatment: - Systemic
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
incomplete Kawasaki Disease ... Infants ≤6 months ... old on day ≥7 of fever ... echo is positive, treatment ... #Diagnosis #Peds
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
+ MPO-ANCA MEDIUM ... mucositis - Rash ... Vasculitis: • Fevers ... testes -> pain, infarct ... #rheumatology #