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management hematology stratification antibiotics chronic infant leukemia lp pediatrics stepbystep apml brain clinical crypto cryptococcal differentiation ebm evaluation hemeonc lymphocytic
Chronic Neutrophilic Leukemia (CNL) • Signaling Pathway • WHO Dx Critera • Risk Stratification • Treatment
Neutrophilic Leukemia (CNL ... Dx Critera • Risk ... Algorithm Zhuoer ... @ZhuoerXie #CNL ... #oncology
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... an infant with fever ... CRP < 20 mg/L #Diagnosis ... Management #Pediatrics #Peds ... #Febrile #Infant
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... Lymphocytes • Median ... ) B symptoms → fevers ... chemotherapy for low-risk ... uw_IMresidency #CLL
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... empiric antibiotic treatment ... 92.0% and 46.9% #Diagnosis ... Management #Pediatrics #Peds ... Stratification #Fever
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Induce blast cell ... Attempt if high risk ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... management #hematology #oncology
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
or family - Ever ... Medical history ... event, follow ACC algorithm ... one post op Cardiology ... stratification #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
carries a variable risk ... Myelogenous Leukemia (CML ... and reducing the risk ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Diagnosis? ... low glucose) CNS ... are common but fever ... half. absence of fever ... Standard treatment
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