20 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Signs/Symptoms ... fractures • Short ... sleep apnea, cor pulmonale ... #genetics #pathophysiology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
cases Clinical Signs ... years - May have signs ... symptoms of active pulmonary ... decreased reflexes Pathophysiology ... for concomitant pulmonary
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... intrapulmonary vascular ... vascular dilation ... no established medical ... hepatopulmonary #syndrome
Adson's Test for Thoracic Outlet Syndrome

To perform Adson's Test locate the radial pulse.
Have the patient take
Test locate the radial ... Video via @open_michigan ... PhysicalExam #clinical #video ... #vascular #msk ... #orthopedics #sports
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
- Refeeding syndrome ... HF • Moderate pulmonary ... : - Impaired short-term ... AV shunt, renal vascular ... beriberi #nutrition #pathophysiology
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
Hypertension Presence of pulmonary ... m/s • Other signs ... vasodilation and reduced vascular ... who respond to medical ... Hypertension #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Cathepsin G release → vascular ... Imaging: CXR- pulmonary ... APML #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... and diplopia) • Vascular ... Medium and large ... #diagnosis #management ... #signs #symptoms
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Seizures • Altered mental ... Presentation: • Altered mental ... Etiology: • Pathophysiology ... cortical lesions • Vascular ... #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary ... #Signs #Symptoms