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differential hematology table vasculitis anticholinergics arteritis behcet classification disease gca giantcell hemophagocytic hlh leukostasis lymphohistiocytosis lysis neurolepticmalignant nms opioids pathophysiology
Signs and Symptoms of Toxidromes Sympathomimetic / GABAergic withdrawal Cholinergic Anticholinergic Opioid withdrawal Neuroleptic malignant syndrome Serotonin
Signs and Symptoms ... Neuroleptic malignant syndrome ... Serotonin syndrome ... #Toxidromes #Comparison ... Sympathomimetics #Diagnosis
Clinical Manifestations of Serotonin Syndrome • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements) • Gastrointestinal: Diarrhea,
Manifestations of Serotonin ... Syndrome • Ophthalmologic ... Akathisia, Altered Mental ... #Syndrome #Symptoms ... #diagnosis
Rapid, increasing signs of extrapyramidal symptoms (EPS) is an important key feature of NMS. EPS, associated
Rapid, increasing signs ... extrapyramidal symptoms ... #Diagnosis #Serotonin ... #Syndrome #NMS ... NeurolepticMalignant #Comparison
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... Medium and large ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... symptoms can mimic ... #management #treatment ... #hematology
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... Syndrome: Variable ... make a clinical diagnosis ... #Psychiatry #Diagnosis ... #Signs #Symptoms
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Involves large and medium ... systemic sx + signs ... them, but urgent rheumatology ... #Symptoms #Diagnosis ... #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
+ MPO-ANCA MEDIUM ... Presentation - Systemic Symptoms ... purpura: strong sign ... aortic aneurysm • Medium ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... primary condition MEDIUM ... • Progressive symptoms ... #Rheumatology
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