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hematology oncology differential leukemia workup aplastic barre chronic cll differentiation disorders encephalopathy gbs guillain lymphocytic mds myelodysplasia myelodysplastic platelet posterior
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... : Blast crises ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... age 70 years Symptoms ... Exposure to heavy metal ... factors (examples: G-CSF ... #diagnosis #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... : >3 symptoms, or ... sepsis), PE, DAH, CHF ... #APML #diagnosis ... #management #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
plateletcount), peripheral ... blood smear, HIV ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... ) Labs: • Peripheral ... result from low blood ... #oncology #hematology ... #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Seizures • Altered mental ... may precede the neurologic ... Neurological symptoms ... #diagnosis #management ... #neurology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... cytometry • Peripheral ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... workup #oncology #hematology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... white blood cell ... than one after symptom ... #diagnosis #management ... #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... pulses, bruits, or blood ... • Progressive symptoms ... tract, and often causes ... #Rheumatology
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