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diagnosis differential management algorithm nephrology pharmacology clinical causes treatment diabetes disease cardiology pocus table pathophysiology rheumatology ultrasound gastroenterology endocrinology biliary
Diabetes Type 2 Medication Management and Titration Algorithm - First line therapy is metformin and comprehensive lifestyle
line therapy is metformin ... Established ASCVD or CKD ... established ASCVD or CKD ... endocrinology #DMII
Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or
Metformin Treatment ... /dc17-2231 #Metformin ... #CKD3 #CKD4 #Dosing
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
Definitions of AKI, CKD ... , AKD Acute Kidney ... Kidney Disease (CKD ... /CKD • No structural ... damage #AKI #CKD
Metformin in Diabetic Kidney Disease Immediate release: • Initial 500 mg or 850 mg once daily •
Metformin in Diabetic ... eGFR < 30: Stop metformin ... do not initiate metformin ... annually if on metformin ... #CKD #pharmacology
Algorithm for Metformin Prescribing and Dosing in CKD Dose Initiation - Immediate release: • Initial 500 mg
Algorithm for Metformin ... and Dosing in CKD ... maximum dose #Metformin ... Prescribing #Dosing #CKD
Management of Diabetes Mellitus in Patients With CKD 1. Monitor for changes in BP, serum creatinine, &
Patients With CKD ... FDA recommends, metformin ... per 1.73 m2 with metformin ... #Diabetes #CKD # ... eGFR #Insulin #metformin
Patient factors influencing the selection Of glucose-lowering drugs Other than SGLT2i and metformin in T2D and
than SGLT2i and metformin ... in T2D and CKD. ... cardiovascular disease: CKD ... , #KDIGO2020 #CKD ... Management in CKD
Diabetes Medications Summary Table Insulin Lifestyle modifications Metformin Sulfonylureas GLP-1 receptor agonists - ↓ major adverse CV events TZDs DPP-4 inhibitors SGLT2 inhibitors -
modifications Metformin ... Improved outcomes in CKD
Diabetes Combination Tablets - Estimated A1c Lowering Metformin + DPP4 • Janumet (metformin + sitagliptin) •
A1c Lowering Metformin ... DPP4 • Janumet (metformin ... • Jentadueto (metformin ... • Kombiglyze (metformin ... saxagliptin) Metformin
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD EMPA-REG OUTCOME - Empagliflozin lowered CV events
and CKD EMPA-REG ... SGLT2i in HF and CKD ... SGLT2i in HF and CKD ... kidney events in CKD ... patients with CKD
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