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Type B Lactic Acidosis Elevated lactic acid when no systemic hypoperfusion is apparent Causes: • Drugs (metformin, linezolid,
Type B Lactic Acidosis ... Elevated lactic ... hypoperfusion is apparent Causes ... : • Drugs (metformin ... #Acidosis #causes
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... e.g. diarrhea, nausea ... about causing lactic ... EricsMedicalLectures/ #Metformin
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Elevation, Lactic ... contribute to lactic ... Elevation Type A Lactic ... and Toxins: - Metformin ... clearance #Lactate #Lactic
Lactic Acidosis Classification - Type A vs Type B Type A Lactic Acidosis: Sepsis, Ischemic bowel, Hemorrhagic
Lactic Acidosis ... Type B Type A Lactic ... Cardiogenic shock Type B Lactic ... Renal failure, Metformin ... transcriptases, Linezolid #Lactic
Metformin Current Renal Dose Adjustments due to Risk of Lactic Acidosis > 60 No adjustment 45-60
Metformin Current ... due to Risk of Lactic ... already taking metformin ... /ambcarerx #Metformin
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
Metformin Associated ... Lactic Acidosis ... Pathophysiology of MALA - Metformin ... concentrations > 5 μg/mL, metformin ... Kat_Watson #MALA #Metformin
Anion Gap Metabolic Acidosis • Diabetic Ketoacidosis ± Hyperglycemia ± Hyperosmolar • Alcoholic Ketoacidosis ± Hyperglycemia
glycol • Type B lactic ... Drugs ( Albuterol, Metformin
Lactic Acidosis - Classification and Differential Diagnosis Type A Lactic Acidosis: Inadequate Oxygen Delivery • Anaerobic muscular
Lactic Acidosis ... Diagnosis Type A Lactic ... Anemia Type B Lactic ... Lactate-based dialysate, Metformin ... 0885066620982585 #Lactic
Kussmaul Breathing in Lactic Acidosis Acute non-cardiopulmonary dyspnoea. 70 ys, DM, vomiting and URQ abdominal pain since
Kussmaul Breathing in Lactic ... BGA: severe lactic ... regularly taken metformin
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 Diabetes Combination Tablets - Estimated A1c Lowering Metformin + DPP4 • Janumet (metformin + sitagliptin) •
A1c Lowering Metformin ... DPP4 • Janumet (metformin ... • Jentadueto (metformin ... • Kombiglyze (metformin ... saxagliptin) Metformin
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