130 results
Apixaban Dose Adjustments in Atrial Fibrillation - ABCDs

Age > 80 years 
Body Weight <60kg 
Creatinine >=
Creatinine >= 1.5 mg ... /dL DOUBLE of ... 5mg bid to 2.5 mg ... #Pharmacology #Dosing
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Uric acid ≥ 8.0 mg ... /dL • Potassium ... ≥ 6.0 mEq/dL ... Phosphorus ≥ 4.6 mg ... ≤ 7.0 mg/dL Clinical
Hypomagnesemia (Serum level < 1.7 mg/dL)
Neuromuscular manifestations 
 • Tremor, tetany, seizures 
 • Weakness
Serum level < 1.7 mg ... /dL) Neuromuscular ... Hypomagnesemia #Signs
Management Algorithm for Status Epilepticus

• Assess airway, breathing, and circulation
• Pulse oximetry
• Electrocardiogram
• Finger stick (give
if glucose < 60 mg ... /dL) • Aspiration ... o Diazepam 5 mg ... to a max of 20 mg ... #pharmacology #dosing
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... Bilirubin: <5 mg ... /dL • Hepatic ... Bilirubin: <5 mg ... /dL unless massive
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Uric acid ≥ 8 mg ... /dL • Potassium ... /dL • Calcium ... ≤ 7 mg/dL • OR ... Treatment of Clinical
Electrolyte Repletion

Significant electrolyte depletion can result in serious complications. These guidelines are meant to assist with
assist with empiric dosing ... concentration 2.0 – 2.4 mg ... /dL Goal serum ... concentration 2.7 – 4.6 mg ... /dL IV electrolyte
Vertical (Upbeat) Nystagmus on Physical Exam

This patient had severe hypomagnesemia. Serum Mg 0.1 mg/dl.

Dr. Arvind Canchi
Serum Mg 0.1 mg/ ... dl. ... hypomagnesemia #clinical
Flexor Tenosynovitis (FTS)

The clinical diagnosis of FTS is made using Kanavel’s Signs:
 - Fusiform swelling.
 -
Tenosynovitis (FTS) The clinical ... of FTS is made using ... Kanavel’s Signs ... Kanavels #Criteria #Sign
Adult Vancomycin Guidelines
The information below provides general dosing guidelines for vancomycin. A maintenance regimen of 15-20
provides general dosing ... regimen of 15-20 mg ... is the accepted dosing ... There is no clinical ... AUC: MIC ratio.1 Dosing