10 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... PE, DAH, CHF, Anaphylaxis ... #diagnosis #management ... #hematology #oncology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... Sepsis (→ 3-14) e.g ... Allergic reaction / anaphylaxis ... Anesthesiology #Anesthesia #Checklist ... #Diagnosis #Management
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia
Tachycardia in theatre is often due to inadequate depth
remember to tailor treatment ... obtain 12-lead ECG ... amniotic (→ 3-5); anaphylaxis ... Intraoperative #Checklist ... #Diagnosis #Management
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
treatment pack ... require prolonged treatment ... alternate vasopressor (e.g ... Intraoperative #Checklist ... #Diagnosis #Management
Cardiac Arrest - Guidelines for Crises in Anaesthesia

The probable cause is one or more of: something
reservoir bag and APL ... • Check ECG rhythm ... 10) Acidosis Anaphylaxis ... CardiacArrest #Checklist ... #Diagnosis #Management
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
reservoir bag and APL ... and positioning (e.g ... ischaemia → 3-12 o Anaphylaxis ... Intraoperative #Checklist ... #Diagnosis #Management
Increased Airway Pressure - Guidelines for Crises in Anaesthesia

Using these steps from start to end should
reservoir bag and APL ... blood gas, 12-lead ECG ... Bronchospasm → 3-4 o Anaphylaxis ... Intraoperative #Checklist ... #Diagnosis #Management
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
remember to tailor treatment ... reservoir bag and APL ... known drug causes (eg ... Intraoperative #Checklist ... #Diagnosis #Management
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Splenomegaly Diagnosis ... transformation into MDS or AML ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
Intraoperative Hypoxia / Desaturation / Cyanosis - Guidelines for Crises in Anaesthesia
Using these steps from start
blood gas, 12-lead ECG ... Bronchospasm → 3-4 o Anaphylaxis ... Intraoperative #Checklist ... #Diagnosis #Workup ... #Management #Workup