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differential rheumatology dermatology algorithm approach autoimmune basics chronic classification cryoglobulinemia cryoglobulins fatigue fever fuo gap globulin joint lesions management msk
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Blood Cell (RBC) Morphology ... Atlas • Microcytic ... Myelodysplastic syndrome ... #Atlas #key #diagnosis ... #differential #hematology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
- Differential Diagnosis ... Lemierre's syndrome ... Malignancy: - Hematologic ... Lupus, Rheumatoid arthritis ... #Differential #Diagnosis
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... • Rheumatoid Arthritis ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... arthralgia, and arthritis ... Labs/Diagnosis: ... tissue disorder (e.g
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... • Key point: If ... Like in this case ... #approach #workup ... #differential #diagnosis
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... Rule out other causes ... antiinflammatory properties e.g ... diagnosis #management ... #Dermatology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... nettle sting #Diagnosis ... #Dermatology #Skin ... #Nomenclature #Atlas ... #Key #Basics
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... (RA, Temporal arteritis ... #differential #diagnosis ... #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... myopathies Diagnostic ... Aldolase levels • EMG ... • Nonerosive arthritis ... statins - probably caused
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