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differential anemia rheumatology oncology algorithm causes hemolytic key macrocytic management microscopy testing vasculitis acquired agglutinin arthritis bloodcell bloodsmear chronic cll
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
RBC) Morphology ... Atlas • Microcytic ... #Morphology #Atlas ... #key #diagnosis ... #differential #hematology
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
and Associated Diseases ... #RedBloodCell #Morphology ... Morphologies #Key #Atlas ... Microscopy #Pathology #Hematology ... #Diagnosis #Dyspmorphic
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology ... Unstable hemoglobin disorders ... Target Cell RBC ... #diagnosis #hematology ... #microscopy #atlas
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell ... other reproducible morphologic ... membrane disorder ... #Algorithm #workup ... #hematology #testing
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... lymphoproliferative disorders ... • Intrinsic RBC ... . sickle cell disease ... #hematology #anemia
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Mean corpuscular (cell ... (BM) ablative disorders ... of substrate (e.g ... #Workup #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... function test, ANA (e.g ... #Causes #Workup ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... can indicate disease ... lymphoproliferative disorders ... #workup #oncology ... #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... - Diagnosis and ... thrombocythemia), Autoimmune disease ... adsorption onto cancer cells ... #treatment #hematology
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