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differential rheumatology algorithm anemia causes dermatology oncology chronic hemolytic macrocytic microscopy nomenclature testing approach autoimmune basics bloodcell bloodsmear cell classification
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
#RedBloodCell #Morphology ... #Morphologies #Key ... #Atlas #Microscopy ... #Pathology #Hematology ... #Diagnosis #Dyspmorphic
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... #Morphology #Atlas ... #key #diagnosis ... #differential #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... Chemotherapy (e.g ... Unstable hemoglobin disorders ... #diagnosis #hematology ... #microscopy #atlas
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (BM) ablative disorders ... of substrate (e.g ... Anemia #Algorithm #Diagnosis ... #Workup #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... function test, ANA (e.g ... #Causes #Workup ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... other reproducible morphologic ... membrane disorder ... #Algorithm #workup ... #hematology #testing
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Increased Requirement (e.g ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... lymphoproliferative disorders ... • Intrinsic RBC ... #hematology #anemia
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
arthralgia, and arthritis ... Labs/Diagnosis: ... (e.g. systemic ... SLE), rheumatoid arthritis ... Cryoglobulins #diagnosis
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... • Rheumatoid Arthritis ... • Drug Abuse (e.g ... • Somatization Disorder ... Chronic Fatigue Syndrome
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