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differential rheumatology algorithm approach autoimmune bloodcell causes cll dermatology disease erythematosus fatigue gap globulin joint laboratory leukemia lupus lymphocytic management
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... #Morphology #Atlas ... #key #diagnosis ... #differential #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... Chemotherapy (e.g ... Unstable hemoglobin disorders ... #diagnosis #hematology ... #microscopy #atlas
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... • Rheumatoid Arthritis ... • Drug Abuse (e.g ... • Somatization Disorder ... Fatigue Syndrome
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... rheumatic fever • Chronic ... • Key point: If ... #approach #workup ... #differential #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... . hematologic) ... titers > 1:80 • CBC ... with Lupus: • Chronic ... Erythematosus #Diagnosis
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic ... inflammatory disorder ... Autoinflammatory disorder ... nonerosive inflammatory arthritis ... antiinflammatory properties e.g
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Lymphocytosis on CBC ... lymphoproliferative disorders ... #workup #oncology ... #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for Chronic ... metabolic or endocrine disorders ... #laboratory #workup ... #diagnosis #testing
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... Connective tissue disorders ... (RA, Temporal arteritis ... #differential #diagnosis
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... Aldolase levels • EMG ... • Nonerosive arthritis ... muscular atrophy • Chronic ... Other Diseases: • PBC
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