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differential anemia disease hemolytic oncology rheumatology agglutinin algorithm arthritis bloodcell causes chronic cold disorders erythematosus key laboratory leukemia lupus lymphocytic
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
RBC) Morphology ... Atlas • Microcytic ... #Morphology #Atlas ... #key #diagnosis ... #differential #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology ... Chemotherapy (e.g ... Bite Cell RBC: G6PD ... #diagnosis #hematology ... #microscopy #atlas
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Consider sickle cell ... other reproducible morphologic ... #Algorithm #workup ... #hematology #testing
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
sweats • Extreme fatigue ... Diagnosis: • ... Lymphocytosis on CBC ... #workup #oncology ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... smear, HIV/HCV testing ... (CVID, WAS), (neurologic ... #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... anemia include fatigue ... Positive Coombs testing ... Blood smear - RBC ... hemolytic #anemia #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Symptoms: • Fatigue ... Workup: • Complete ... Treatment: Goals: Treating ... #diagnosis #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for All ... (to support a diagnosis ... Arthritis #laboratory #workup ... #diagnosis #testing
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Clinical evidence of (fatigue ... Differential Diagnosis ... vein thrombosis Hematologic ... titers > 1:80 • CBC ... Erythematosus #Diagnosis
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